Isotopic Labelled Analogues

The isotopic labelled analogues are primarily utilized as internal standards (stable isotope-labeled internal standards (SILISs)) alongside targets with active groups. These are synthesized by utilizing precursors where at least one particle has been supplanted with a purified isotopic analogue. Hence, it is “labelled” with isotopes at different sites within the molecule. The analogues and analytes have the same chemical formula yet differ from each other based on their masses. The isotopic labelled analogues are considered to be an important asset for minimizing measurement uncertainty and precise quantification by coupling it with electrospray LC-MS. It is required to rightly select and optimize these analogues for any given application which also needs a degree of technical knowledge and scientific assessment. A wide range of isotopic labelled analogues is available to purchase online on Biomall.in.