(-)-Epigallocatechin Gallate inhibits cellular oxidation of low density lipoproteins. It also inhibits the peroxynitrite-induced formation of the oxidative injury markers 8-hydroxy-2-deoxy guanosine and 3-nitrotyrosine, apoptosis in human prostate cancer cells. Selectively inhibits activation of JNK/SAPK signaling pathway and suppresses proliferation of vascular smooth muscle cells. Shows growth inhibitory effects on tumor cells but not their normal counterparts. Inhibits telomerase. A fast-binding and reversible fatty acid synthase inhibitor. Inhibits PMA-induced skin thickening. Inhibits activation of interleukin-1 mRNA and protein expression. Inhibits nitric oxide synthase (iNOS) gene expression. At M concentrations, it inhibits VEGF-induced tyrosine phosphorylation.