Twin-NX technology HPLC columns. Extend your column lifetime

Gemini columns are rugged reversed phase HPLC and PREP LC columns that offer extended lifetime at pH 1-12 conditions and excellent stability for reproducible, high efficiency separations. The Gemini family contains a variety of useful akyl and phenyl phases bonded to fully porous organo-silica particles.

Reversed Phase

Gemini C18 Phase

Gemini C18 HPLC phase offers unique reversed phase selectivity, high structural integrity, and increased loadability which make it ideal for preparative and purification applications in pre-packed columns and bulk media.

Gemini C6-Phenyl Phase

Gemini C6-Phenyl HPLC phase has a phenyl group bound to the organo-silica surface using a 6-carbon chain for a low bleed aromatic selective phase. Gemini C6-Phenyl is well suited for LC/MS applications.

Gemini NX-C18 Phase

The most rugged and highly efficient Gemini C18 HPLC column phase for reversed phase. Gemini NX-C18 takes LC/MS separations to the next level and offers:

• Control selectivity of ionizable compounds for optimized methods
• Consistent performance in both volatile and non-volatile buffers
• High and low pH methods

Gemini C8(3) Phase

Optimized Purification Media for Human Insulin and It's Analogues

• Enhanced Robustness Against Caustic Regeneration Conditions
• High Packing Efficiencies
• Incredible Mechanical Strength

Typically insulin purification methodologies include vital steps for column efficiency tests, equilibration, loading, and multiple caustic washes. In particular, the high pH caustic washes are very important for the removal aggregate build up, however these wash steps typical diminish column lifetime quite substantially. With the improved chemical robustness and performance of Gemini C8(3) customers can now switch their focus to higher yields and purities and minimize operational down-time due to less frequent need to replace contaminated media.

QC Tested to ensure consistent selectivity for Insulin and Impurity

In conjunction with a media designed specifically for insulin purification, the Quality team at Phenomenex strives to ensure high reproducibility of Gemini 10m C8(3) through numerous quality control steps throughout the manufacturing process, including a fit for purpose human insulin QC test. This elevated level of focus on quality ultimately results in a model product for large scale insulin purification.