Cirrhosis is condition occurred due to long term malfunctioning of liver. Hepatocytes isolated from cirrhotic liver can help identifying cause of disease, progression disease and in many other conditions. Pathophysiology of liver cirrhosis can be studied using hepatocytes isolated from diseased liver.Diseased Liver Hepatocytes are derived from primary diseased liver cells. Left liver lob is generally used for isolation of these cells. These cells express cytokeratin 18 and albumin in early passage. Diseased Liver Hepatocytes are derived from primary diseased liver cells. Left liver lob is generally used for isolation of these cells. These cells express cytokeratin 18 and albumin in early passage.