Multisizer 4e Coulter Counter Overview

The Multisizer 4e particle sizer and counter is the most accurate and flexible particle characterization device available, boasting an unparalleled sizing range of 0.2 - 1600 m. The new 10 m Aperture allows users to study sub-cellular and micro-particles as small as 200 nm, while the advanced noise reduction system for small apertures improves measurement accuracy.

Generated data are processed using patented digital pulse processing technology and can be saved and later re-analyzed. This technology provides ultra high resolution and accuracy unattainable through any other technologies: detection of 1 particle in 1 ml of a sample with the optimal instrument configuration. Analysis results are not dependent on particle shape, structure, or optical properties.

It uses the Coulter principle to detect particles via electrical zone sensing, regardless of the particles nature or optical properties. This makes it an ideal tool for detecting and counting a wide variety of particles, such as:

• Mammalian cells
• Bacteria
• Yeast
• Abrasives
• Toner particles
• Cell aggregates
• Spheroids
• Large protein aggregates

Features

Versatility

• Aperture sizes from 10 m - 2000 m in diameter for current & future needs
• Multiple aperture options & data overlay capability for analyzing complex samples over wide particle size distribution

Sample Detection

• Analyze materials in aqueous or non-aqueous solvents
• Ideal for biological or non-biological samples
• Detect particles regardless of material type or optical properties

Rapid Particle Counting

• Typical sampling rates up to 10,000 counts per second
• Detect & count particles from 0.2 m - 1600 m in diameter
• Sample volumes as small as 5 mL

Data Management

• Digital pulse data can be stored & re-analyzed as needed
• CFR 21 Part 11 compliant software for audit control & security
• Variety of calibration beads & V-check validation controls