Protein Arginine Methyltransferases (PRMTs) are S-adenosyl-L-methionine-dependent enzymes that catalyze post-translational modification of arginine residues by methylation in three different ways: monomethylation, symmetric dimethylation, or asymmetric dimethylation at terminal arginine guanidino nitrogen atoms.1 Class I PRMTs catalyze arginine monomethylation and asymmetric dimethylation. PRMT1 is a class I arginine methyltransferase that methylates arginine residues at a number of glycine and arginine rich regions (GAR motifs) in proteins including histone H4 at arginine 3.2Technical InformationSynonymsInterferon receptor 1-bound protein 4Protein Arginine Methyltransferase 1Purity35% estimated by SDS-PAGESourceActive recombinant N-terminal GST-tagged protein expressed in E. coliAmino Acids2-371 (full-length)MW69.2 kDaUniProt Accession Q99873