Protamine Sulfate is a raw materials for lab to study preparations like insulin compounds, etc. It is used in separation and refining of vaccines. It is a reagents for removing nucleic acids from enzyme solution for the purpose of easy separation and refining. Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.