TOFACITINIB CITRATE is supplied by Sigma-Aldrich. It is a synthetic molecule that is utilized:

• as a ligand for human serum albumin in fluorescence quenching, dynamic light scattering (DLS) measurements, differential scanning calorimetry and molecular docking studies
• as a medium supplement for full depth articular cartilage (FDC) explants to monitor cytokine-induced proteoglycan loss
• as a Janus kinase inhibitor in MCF7 breast cancer cells

PRODUCT SPECIFICATIONS:

• Name: TOFACITINIB CITRATE
• Category: Fine chemicals
• Brand: Sigma-Aldrich
• Pack size: 5MG
• Catalog number: PZ0017-5MG
• List price: 10445.1

PRODUCT FEATURES:

• Synonym: (3R,4R)-4-Methyl-3-(methyl-7H-pyrrolo[2,3-d]pyrimidin-4-ylamino)--oxo-1-piperidinepropanenitrile citrate salt, 3-[(3R,4R)-4-Methyl-3-[methyl-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]piperidin-1-yl]-3-oxopropanenitrile citrate salt, CP-690550-10, Tasocitinib citrate salt
• CAS Number: 540737-29-9
• Empirical Formula: C16H20N6O C6H8O7
• Molecular Weight: 504.49 Assay: 98% (HPLC)
• Form: powder
• Color: white to beige
• Solubility: DMSO: 5 mg/mL (clear solution; warmed)
• Storage temperature: room temperature